論文一覧

Liu Y, Ikawa T, Tada Y, Tanaka T, Ohnishi T, Watanabe S, Tsukui D, Asako K, Kono H.
Two Severe Cases of Adult-onset Still’s Disease with Persistent Pruritic Eruptions.
Acta Derm Venereol. doi: 10.2340/00015555-2887. 2018

Tsukui D, Kono H.
Ultraviolet Purpura in IgA Vasculitis.
Mayo Clin Proc. 93(1):122, 2018

Kawasaki A, Yamashita K, Hirano F, Sada KE, Tsukui D, Kondo Y, Kimura Y, Asako K, Kobayashi S, Yamada H, Furukawa H, Nagasaka K, Sugihara T, Yamagata K, Sumida T, Tohma S, Kono H, Ozaki S, Matsuo S, Hashimoto H, Makino H, Arimura Y, Harigai M, Tsuchiya N.
Association of ETS1 polymorphism with granulomatosis with polyangiitis and proteinase 3-anti-neutrophil cytoplasmic antibody positive vasculitis in a Japanese population.
J Hum Genet. 63(1):55-62, 2018

Kimura Y, Asako K, Kikuchi H, Kono H
Refractory optic perineuritis due to granulomatosis with polyangiitis successfully treated with methotrexate and mycophenolate mofetil combination therapy.
Eur J  Rheumatol. 4(1):70-72, 2017

Abe G, Kikuchi H, Arinuma Y, Hirohata S
Brain MRI in patients with acute confusional state of diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematous.
Modern rheumatol. 27(2):278-283, 2017

Morimoto C, Fujigaki Y, Tamura Y, Ota T, Shibata S, Asako K, Kikuchi H, Kono H, Kondo F, Yamaguchi Y, Uchida S. Emergence of Smoldering ANCA-associated Glomerulonephritis During the Clinical Course of Mixed Connective Tissue Disease and Sjögren’s Syndrome.
Intern Med.  doi:10.2169/internalmedicine.9844-17.  2017

Hachiya Y, Kawasaki A, Oka S, Kondo Y, Ito S, Matsumoto I, Kusaoi M, Amano H, Suda A, Setoguchi K, Nagai T, Shimada K, Sugii S, Okamoto A, Chiba N, Suematsu E, Ohno S, Katayama M, Kono H, Hirohata S, Takasaki Y, Hashimoto H, Sumida T, Nagaoka S, Tohma S, Furukawa H, Tsuchiya N.
Association of HLA-G 3′ Untranslated Region Polymorphisms with Systemic Lupus Erythematosus in a Japanese Population: A Case-Control Association Study.
PLoS One. 11(6):e0158065. 2016

Onda A, Kono H, Jiao Q, Akimoto T, Miyamoto T, Sawada Y, Suzuki K, Kusakari Y, Minamisawa S, Fukubayashi T.
New mouse model of skeletal muscle atrophy using spiral wire immobilization.
Muscle Nerve. 54(4):788-91, 2016

Furukawa H, Oka S, Kawasaki A, Shimada K, Sugii S, Matsushita T, Hashimoto A, Komiya A, Fukui N, Kobayashi K, Osada A, Ihata A, Kondo Y, Nagai T, Setoguchi K, Okamoto A,  Chiba N, Suematsu E, Kono H, Katayama M, Hirohata S, Sumida T, Migita K, Hasegawa M, Fujimoto M, Sato S, Nagaoka S, Takehara K, Tohma S, Tsuchiya N. Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01.
PLoS One. 11(4):e0154255. 2016

Kimura Y, Asako K, Kikuchi H, Kono H.
Characteristics of patients with intestinal Behçet’s disease requiring treatment with immunosuppressants or anti-TNFα antibody.
Mod Rheumatol. 26(1):132-137, 2016

Hibi T, Hirohata S, Kikuchi H, Tateishi U, Sato N, Ozaki K, Kondo K, Ishigatsubo Y
Infliximab therapy for intestinal, neurological and vascular involvement in Behcet disease:Efficacy, safety, and pharmacokinetics in a multicenter, prospective, open-label, single-arm phase 3 study.
Medicine. 95(24):e3863, 2016

Kimura Y, Asako K, Kikuchi H, Hoshimoto K, Sasajima Y, Kono H
Relapsing Polychondritis Complicated by Vasculitis of the Omentum.
Internal Medicine. 55(10):1363-1366, 2016

Nakano R, Nakano A, Ishii Y, Ubagai T, Kikuchi-Ueda T, Kikuchi H, Tansho-Nagakawa S, Kamoshida G, Mu X, Ono Y.
Rapid detection of the Klebsiella pneumoniae carbapenemase (KPC) gene by loop-mediated isothermal amplification (LAMP).
J Infect Chemother. 21(3):202-6, 2015

Hirohata S, Kikuchi H, Sawada T, Nagafuchi H, Kuwana M, Takeno M, Ishigatsubo Y.
Retrospective analysis of long-term outcome of chronic progressive neurological manifestations in Behcet’s disease.
J Neurol Sci. 349(1-2):143-8, 2015

Kamoshida G, Kikuchi-Ueda T, Tansho-Nagakawa S, Nakano R, Nakano A, Kikuchi H, Ubagai T, Ono Y.
Acinetobacter baumannii escape from neutrophil extracellular traps
J Infect Chemother. 21(1):43-9, 2015

Kanno S, Nishio H, Tanaka T, Motomura Y, Murata K, Ihara K, Onimaru M, Yamasaki S, Kono H, Sueishi K, Hara T.
Activation of an innate immune receptor, nod1, accelerates atherogenesis in apoe-/- mice.
J Immunol. 194(2):773-80, 2015

Hirohata S, Kikuchi H, Sawada T, Nagafuchi H, Kuwana M, Takeno M, Ishigatsubo Y.
Analysis of various factors on the relapse of acute neurological attacks in Behçet’s disease.
Mod Rheumatol. 24(6):961-5, 2014

Arinuma Y, Kikuchi H, Wada T, Nagai T, Tanaka S, Oba H, Hirohata S.
Brain MRI in patients with diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosus.
Lupus Sci Med. 1(1):e000050. 2014

Kawasaki A, Furukawa H, Nishida N, Warabi E, Kondo Y, Ito S, Matsumoto I, Kusaoi M, Amano H, Suda A, Nagaoka S, Setoguchi K, Nagai T, Hirohata S, Shimada K, Sugii S, Okamoto A, Chiba N, Suematsu E, Ohno S, Katayama M, Okamoto A, Kono H, Tokunaga K, Takasaki Y, Hashimoto H, Sumida T, Tohma S, Tsuchiya N.
Association of functional polymorphisms in interferon regulatory factor 2 (IRF2) with susceptibility to systemic lupus erythematosus: a case-control association study.
PLoS One. 9(10):e109764. 2014

Kono H, Kimura Y, Latz E.
Inflammasome activation in response to dead cells and their metabolites.
Curr Opin Immunol. 30:91-8, 2014

Kataoka H, Kono H, Patel Z, Kimura Y, Rock KL.
Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses.
PLoS One. 9(8):e104741. 2014

Hajime Kono, Akiko Onda, Tamiko Yanagida
Molecular determinants of sterile inflammation
Cuurent Opin Immunol. 26:147-56, 2014

Furukawa H, Kawasaki A, Oka S, Ito I, Shimada K, Sugii S, Hashimoto A, Komiya A, Fukui N, Kondo Y, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Amano H, Nagai T, Hirohata S, Setoguchi K, Kono H, Okamoto A, Chiba N, Suematsu E, Katayama M, Migita K, Suda A, Ohno S, Hashimoto H, Takasaki Y, Sumida T, Nagaoka S, Tsuchiya N, Tohma S.
Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB1*13:02 and *14:03.
PLoS One. 3;9(2):e87792, 2014

De Nardo D, Labzin LI, Kono HSeki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T,Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E.
High density lipoprotein mediates anti-inflammatory transcriptional reprogramming of macrophages via the transcriptional repressor ATF3
Nat Immunol. 15(2):152-60, 2014

Kikuchi H, Takayama M, Hirohata S.
Quantitative Analysis of Brainstem Atrophy on Magnetic Resonance Imaging in Chronic Progressive Neuro-Behçet’s Disease.
J Neurological Sci. November 28, 2013; doi:10.1016/j.jns. 2013.11.020.

Yokoseki A, Saji E, Arakawa M, Kosaka T, Hokari M, Toyoshima Y, Okamoto K, Takeda S, Sanpei K, Kikuchi H, Hirohata S, Akazawa K, Kakita A, Takahashi H, Nishizawa M, Kawachi I.
Hypertrophic pachymeningitis: significance of myeloperoxidase anti-neutrophil cytoplasmic antibody.
Brain.  November 22, 2013; doi:10.1093/brain/awt314.

Yanagida T, Orihashi K, Kono H.
In vivo evaluation of neutrophil recruitment in response to sterile particulates.
Methods Mol Biol. 1040:211-21, 2013

Nakano R, Okamoto R, Nakano A, Nagano N, Abe M, Tansho-Nagakawa S, Ubagai T, Kikuchi-Ueda T, Koshio O, Kikuchi H, Ono Y.
Rapid assay for detecting gyrA and parC mutations associated with fluoroquinolone resistance in Enterobacteriaceae.
J Microbiol Methods. 94(3):213-216, 2013

Furukawa H, Oka S, Shimada K; Rheumatoid Arthritis-Interstitial Lung Disease Study Consortium, Tsuchiya N, Tohma S.
HLA-A*31:01 and methotrexate-induced interstitial lung disease in Japanese rheumatoid arthritis patients: a multidrug hypersensitivity marker?
Ann Rheum Dis. 72: 153-5, 2013.

Hirohata S, Kikuchi H.
Changes in biomarkers focused on differences in disease course or treatment in patients with neuro-Behçet’s disease.
Intern Med. 51:3359-65, 2012

Kikuchi H, Asako K, Tansho S, Ueda T, Koshio O, Ubagai T, Asahara M, Kawakami S, Ono Y.
Recurrent Helicobacter cinaedi cellulitis and bacteremia in a patient with systemic lupus erythematosus.
Intern Med. 51: 3185-8, 2012

Kono H, Orlowski GM, Zubin P, Rock KL.
The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C.
J Immunol 189: 3734-40, 2012

Tansho-Nagakawa S, Ubagai T, Kikuchi-Ueda T, Koshio O, Koshibu Y, Kikuchi H, Ono Y.
Analysis of membrane antigens on neutrophils from patients with sepsis.
J Infect Chemother. 18: 646-51, 2012

Kikuchi H, Yamamoto T, Asako K, Takayama M, Shirasaki R, Ono Y.
Etanercept for the treatment of intractable hemophagocytic syndrome with systemic lupus erythematosus.
Mod Rheumatol. 22: 308-11, 2012

Hirohata S, Kikuchi H, Sawada T, Nagafuchi H, Kuwana M, Takeno M, Ishigatsubo Y.
Clinical characteristics of neuro-Behcet’s disease in Japan: a multicenter retrospective analysis.
Mod Rheumatol. Sep 21, 2011. DOI: 10.1007/s10165-011-0533-5

Asako K, Takayama M, Kono H, Kikuchi H.
Churg-Strauss syndrome complicated by central retinal artery occlusion: case report and a review of the literature.
Mod Rheumatol. 21 : 519-23, 2011.

Hirohata S, Nagai T, Asako K, Tomita T, Yoshikawa H.
Induction of type B synoviocyte-like cells from plasmacytoid dendritic cells of the bone marrow in rheumatoid arthritis and osteoarthritis.
Clin Immunol. 140: 276-83, 2011.

Arinuma Y, Kikuchi H, Aramaki K, Kyogoku M, Hirohata S.
Histopathological analysis of cerebral hemorrhage in systemic lupus erythematosus complicated with antiphospholipid syndrome.
Mod Rheumatol. 21: 509-13, 2011.

Nagatani K, Komagata Y, Asako K, Takayama M, Yamamoto K.
Antigen-specific regulatory T cells are detected in Peyer’s patches after the interaction between T cells and dendritic cells loaded with orally administered antigen.
Immunobiology. 216: 416-22, 2011.

Rock KL, Lai JJ, Kono H.
Innate and adaptive immune reponses to cell death.
Immunol Rev. 243: 191-205, 2011.

Duewell P#, Kono H# Rayner K, Sirois CM, Vladimer G, Bauernfeind FG, Rock KL, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Moore KJ, Wright SD, Hornung V#, Latz E# (# equal contribution).
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature 464: 1357-1361, 2010

Kono H, Chen CJ, Ontiveros F, Rock KL.
Uric acid promotes an acute inflammatory response to sterile cell death in mice.
J Clin Invest. 120: 1939-1949, 2010

Kono H, Karmarkar D, Iwakura Y, Rock KL.
Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.
J Immunol. 184: 4470-4478, 2010

Rock KL, Latz E, Ontiveros F, Kono H.
The sterile inflammatory response.
Annu Rev Immunol. 28: 321-342, 2010

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